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Hexarelin acetate (also known as examorelin) is a synthetic six-amino-acid peptide classified as a growth hormone secretagogue (GHS). Instead of supplying growth hormone directly, it stimulates the pituitary gland and hypothalamus to release the body's own growth hormone.
Key Facts
• Mechanism: It acts as a ghrelin receptor (GHS-R1a) agonist, binding to receptors in the brain to trigger growth hormone pulses.
• Research vs. Reality: While studied in laboratory and animal settings for muscle preservation, bone density, lipid metabolism, and potential cardiovascular protection, robust long-term human safety and efficacy data are lacking.
• Side Effects: It can elevate levels of cortisol, ACTH, and prolactin, and may cause localized or systemic reactions