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Livagen is a synthetic tetrapeptide bioregulator with the sequence Lys-Glu-Asp-Ala (KEDA). Developed in Russia as part of the Khavinson class of short peptides, it is studied primarily for its effects on liver and immune function.
Key Characteristics & Mechanism
• Sequence: Four amino acids—Lysine (Lys), Glutamic Acid (Glu), Aspartic Acid (Asp), and Alanine (Ala).
• Chromatin Remodeling: Research suggests Livagen induces decondensation of heterochromatin in aging cells, potentially re-activating silenced genes and supporting protein synthesis in older tissues.
• Target Systems: Investigated for liver (hepatocyte) support, immune cell markers, and modulation of enkephalin-degrading enzymes.